Publications by authors named "M Fesneau"

Purpose: The main objective of this study was to evaluate the 5-year efficacy of exclusive laryngeal radiotherapy without node prophylactic irradiation for localized cancers of the vocal cords.

Patients And Methods: We retrospectively reviewed charts from 258 patients with T1-T2N0 glottic carcinoma irradiated from April 1987 to March 2015 in four France western centers, including pretreated patients. Toxicity was analyzed according to CTCAE v4.

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Epithelioid hemangioendothelioma is a rare vascular tumour, with features between hemangiomas and angiosarcomas. Evolution remains mainly local but may also metastasize. Here, we report a case of a patient with a spinal epithelioid hemangioendothelioma.

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Article Synopsis
  • - The study focused on the clinical significance of 9p allelic loss in anaplastic oligodendroglial tumors (AOTs) that have a 1p/19q codeletion and analyzed data from 216 patients.
  • - Researchers found that a specific area of loss on chromosome 9 (9p21.3) occurred in 41.7% of tumors, and this was linked to poorer survival rates for patients in multiple analyses.
  • - The findings suggest that 9p allelic loss could serve as a new prognostic biomarker for AOTs, highlighting the need for further research to explore this potential.
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Anal canal epidermoid carcinomas represent 1.2% of digestive cancers and 6% of ano-rectal cancers. For localized diseases, the treatment is based on radiotherapy with or without chemotherapy (5-FU and cisplatin or mitomycin), according to tumour and nodal extension.

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Purpose: Concomitant chemoradiotherapy is the standard treatment of locally advanced, nonresectable, head-and-neck squamous cell carcinoma. However, the optimal chemotherapy regimen is still controversial. The objective of this Phase II study was to evaluate the feasibility and efficacy of a concomitant treatment using tegafur-uracil, leucovorin, carboplatin, and radiotherapy.

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