Dietary Carrageenan Amplifies the Inflammatory Profile, but not Permeability, of Intestinal Epithelial Cells from Patients With Crohn's Disease.

Background: The consumption of ultra-processed foods has increased significantly worldwide and is associated with the rise in inflammatory bowel diseases. However, any causative factors and their underlying mechanisms are yet to be identified. This study aimed to further elucidate whether different types of the dietary emulsifier carrageenan (CGN) can alter the permeability and inflammatory state of the intestinal epithelium.

Synthesis and characterization of gelatin/chondroitin sulfate microgels with NaCl: Preliminary research toward wound healing applications.

Gelatin and chondroitin sulfate are natural polymers with significant potential in the biomedical field, particularly for wound healing applications. They can form hydrogels that absorb exudates and exhibit anti-inflammatory and antioxidant properties. Silver nanoparticles (AgNPs) can be used as antibacterial agents in wound management.

Evolution of Eligibility Criteria in Inflammatory Bowel Disease Clinical Trials: A Clinical Trial Databank Analysis.

Background: Eligibility criteria in clinical trials have been criticised for being overly restrictive without clinical justification.

Objective: We aimed to investigate the types, evolution, and current status of eligibility criteria in clinical trials for inflammatory bowel diseases (IBD).

Methods: We performed a clinical trial databank search on clinicaltrials.