Epidemiological and Molecular Surveillance of Leishmania Species among Humans, Vectors, and Dogs in a Wildland-Urban Interface of Cartagena, Colombia.

In Colombia, human leishmaniasis is endemic in rural areas, with increasing reports of outbreaks and cases in urban areas. Cartagena, an urban city in the Colombian Caribbean with a wildland-urban interface, faced its first local cases between 2011 and 2015. Despite reports, visceral leishmaniasis (VL) remains neglected and understudied and almost devoid of active surveillance.

COVID-19 clinical phenotypes in vaccinated and nonvaccinated solid organ transplant recipients: a multicenter validation study.

Clinical phenotypes of COVID-19, associated with mortality risk, have been identified in the general population. The present study assesses their applicability in solid organ transplant recipients (SOTR) hospital-admitted by COVID-19. In a cohort of 488 SOTR, nonvaccinated (n = 394) and vaccinated (n = 94) against SARS-CoV-2, we evaluated 16 demographic, clinical, analytical, and radiological variables to identify the clinical phenotypes A, B, and C.

Spatially resolved dual-comb sensing with a single electro-optic modulator.

We demonstrate spatially resolved sensing by a novel approach that combines an infrared camera and a simplified dual-comb illumination arrangement. Specifically, our scheme employs a continuous-wave laser and only one electro-optic modulator to simultaneously create a pair of mutually coherent optical frequency combs, each one with a slightly different line spacing. The system operates by measuring this dual-comb spectrum from a sequence of acquired images, in order to recover the spectral response of every spatial point of a sample.

Performance of a Global Functional Assay Based on Interferon-γ Release to Predict Infectious Complications and Cancer After Kidney Transplantation.

The QuantiFERON-Monitor assay (QTF-Monitor) is intended to assess innate and adaptive immune responses by quantifying interferon (IFN)-γ release upon whole blood stimulation with a TLR7/8 agonist and an anti-CD3 antibody. We performed the QTF-Monitor in 126 kidney transplant recipients (KTRs) at different points during the first 6 post-transplant months. The primary outcome was overall infection, whereas secondary outcomes included bacterial infection, opportunistic infection and cancer.