Background: Assessment of bone marrow infiltration (BMI) is part of the initial staging of mantle cell lymphoma (MCL), although BMI evaluated by biopsy (BMB) is not considered significant in the MIPI scales, and standardized recommendations remain lacking.
Objectives: To evaluate the accuracy and prognostic impact of BMI assessed by PET/CT and BMB in a large series of MCL patients.
Methods: We deconstructed the IPI-NCCN, MIPI, and MIPI-c indices and considered BMI as positive if indicated by a BMB, PET/CT scan, or a combination of both.
Obstacle contact detection is not commonly employed in autonomous robots, which mainly depend on avoidance algorithms, limiting their effectiveness in cluttered environments. Current contact-detection techniques suffer from blind spots or discretized detection points, and rigid platforms further limit performance by merely detecting the presence of a collision without providing detailed feedback. To address these challenges, we propose an innovative contact sensor design that improves autonomous navigation through physical contact detection.
View Article and Find Full Text PDF(1) Background: donor-derived circulating free DNA (dd-cfDNA), an innovative biomarker with great potential for the early identification and prevention of graft damage. (2) Methods: Samples were collected prospectively and the study was performed retrospectively to analyze dd-cfDNA plasma levels in 30 kidney transplant patients during their post-transplant follow-up (15 days, 3, 6, and 9 months), to determine if the result could be of interest in the identification of possible adverse events, especially rejection. The aim was to verify whether the data on sensitivity, specificity, NPV, and PPV compare with reference values and creatinine values.
View Article and Find Full Text PDFThis study presents data on the concentration of spores in the atmosphere of the northwestern Iberian Peninsula. A non-viable volumetric method was used to collect the samples, resulting in a database of 70 annual. When the annual averages for each locality are calculated, Ourense stands out with 2152 spores/m, followed by Vigo and Lugo, while Santiago de Compostela recorded the lowest concentrations.
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