Publications by authors named "M Fernandez-Garces"
VEXAS syndrome is a rare entity secondary to UBA1 gene mutations, located on the X chromosome. This mutation generates, as a consequence, a characteristic vacuolation on haematopoietic stem-cells. It is characterized by multiple autoinflammatory and haematologic manifestations, which respond and end up being dependent on corticosteroid treatment.
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- * A study involving over 14,000 patients revealed that smokers were generally older, predominantly male, and had more underlying health issues, which contributed to their increased risk.
- * The research indicates that both current and former smokers are at a greater risk for complications after being hospitalized for COVID-19, highlighting smoking as a significant factor in disease severity.
(1) Background: C-reactive protein (CRP) and albumin are inflammatory markers. We analyzed the prognostic capacity of serum albumin (SA) and CRP for an outcome comprising mortality, length of stay, ICU admission, and non-invasive mechanical ventilation in hospitalized COVID-19 patients. (2) Methods: We conducted a retrospective cohort study based on the Spanish national SEMI-COVID-19 Registry.
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- Smoking is linked to more severe outcomes in COVID-19 patients, showing increased rates of ICU admissions and in-hospital mortality compared to non-smokers.
- A study of over 14,000 COVID-19 patients in Spain found that smokers were older, predominantly male, and had worse health profiles.
- The research suggests that both current and former smokers face a higher risk of complications from COVID-19, indicating that smoking is a significant factor in determining patient prognosis.
Objectives: Since the results of the RECOVERY trial, WHO recommendations about the use of corticosteroids (CTs) in COVID-19 have changed. The aim of the study is to analyse the evolutive use of CTs in Spain during the pandemic to assess the potential influence of new recommendations.
Material And Methods: A retrospective, descriptive, and observational study was conducted on adults hospitalised due to COVID-19 in Spain who were included in the SEMI-COVID-19 Registry from March to November 2020.