Anti-Xa activity below range is related to thrombosis in patients with severe COVID-19.

Objective: We aimed to anlayse the relationship between anti-Xa activity below range and thomboembolic events.

Design: Single center prospective observational longitudinal cohort study (February-November 2021).

Setting: Patients admitted to the ICU of a University Hospital.

VHrare study: Prevalence, clinical features and management of severe rare bleeding disorders in a large cohort.

Introduction: Rare bleeding disorders (RBD) constitute 5% of total hereditary bleeding disorders, although the number could be higher, due to the presence of undiagnosed asymptomatic patients. The objective of this study was to analyze the prevalence and characteristics of patients with severe RBDs in our area.

Material And Methods: We analyzed the patients with RBD followed at a tertiary-level hospital between January 2014 and December 2021.

Impact of risk scores in outcome of patients with myeloid neoplasms after allogeneic stem cell transplant.

Background: The main causes of failure of allogeneic hematopoietic stem cell transplantation (allo-transplant) in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are relapse and transplant-related mortality. Different scores have been designed to predict the prognosis of these patients. The objective of this study was to assess which score or combination has better outcome predictive capacity.

Heparin versus aspirin thromboprophylaxis adds independent value to IMPEDE-VTE score for venous thrombosis prediction in multiple myeloma.

Multiple myeloma (MM) is associated to an increased incidence of venous thromboembolism (VTE). IMPEDE-VTE score constitutes a valuable risk assessment tool for VTE prediction in first-line MM patients. Nevertheless, refinement of the primary thromboprophylaxis category of this score (which pools aspirin and heparin) seems desirable.