Craniofacial Fibrous Dysplasia: Experience at San José Hospital, Bogotá, Colombia.

Introduction: Fibrous dysplasia is a disorder in which normal bone is gradually replaced by immature fibro-osseous tissue, with an incidence of less than 7% of all benign bone tumors. The management of this disease is a challenge for plastic surgeons and neurosurgeons.

Goal: To describe the diagnostic, therapeutic, and outcome approach of patients with craniofacial fibrous dysplasia seen at the Plastic Surgery Service of the Hospital San José in Bogotá, Colombia.

Emergency Medical Services Protocols for Assessment and Treatment of Patients with Ventricular Assist Devices.

Background: Patients with ventricular assist devices (VADs) represent a growing population presenting to Emergency Medical Services (EMS), but little is known about their prehospital care. This study aimed to characterize current EMS protocols in the United States for patients with VADs.

Methods: States with state-wide EMS protocols were included.

Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.

Background: CD36 has been identified as a potential therapeutic target both in leukemic cells and in the tumor immune microenvironment. In acute myeloid leukemia (AML), we found that APOC2 acts with CD36 to promote leukemia growth by activating the LYN-ERK signaling. CD36 also plays a role in lipid metabolism of cancer associated T-cells leading to impaired cytotoxic CD8 T-cell and enhanced T cell function.

Boosted Random Ferns for Object Detection.

In this paper we introduce the Boosted Random Ferns (BRFs) to rapidly build discriminative classifiers for learning and detecting object categories. At the core of our approach we use standard random ferns, but we introduce four main innovations that let us bring ferns from an instance to a category level, and still retain efficiency. First, we define binary features on the histogram of oriented gradients-domain (as opposed to intensity-), allowing for a better representation of intra-class variability.

p38α limits the contribution of MAP17 to cancer progression in breast tumors.

MAP17 is a small, 17-kDa, non-glycosylated membrane protein that is overexpressed in a percentage of carcinomas. In the present work, we have analyzed the role of MAP17 expression during mammary cancer progression. We have found that MAP17 is expressed in 60% human mammary tumors while it is not expressed in normal or benign neoplasias.