Purpose: To report a case of biopsy-proven sarcoidosis in a patient with panuveitis and a positive interferon-gamma release assay (IGRA) from a non-endemic tuberculosis (TB) country.
Methods: Case report.
Results: A 26-year-old male from the United Arab Emirates (UAE) presented with granulomatous panuveitis characterized by mutton-fat keratic precipitates, anterior chamber and vitreous cells, and retinal vasculitis.
The skin is the most extensive organ in vertebrates, composed of two layers: the epidermis and the dermis. Sensory axons originating from the dorsal root ganglia innervate the skin mechanoreceptors in the dermis. Elasmobranchs, which appeared 380 million years ago, are characterized by rough skin composed of dermal denticles.
View Article and Find Full Text PDF: This review synthesizes the role of () and () in modulating immune responses through citrullination and assesses its impact on periodontitis and systemic conditions. A systematic review was conducted on preclinical and clinical studies focusing on and -induced citrullination and its effects on immune responses, particularly inflammatory pathways, and systemic diseases. The search included PubMed, Scopus, Google Scholar, Web of Science, and gray literature.
View Article and Find Full Text PDFIntroduction: Optimal outcomes during childhood cancer treatment require effective management of toxicities, often called supportive care. A lack of agreement on what comprises supportive care limits the development and provision of comprehensive guidance (for this work, we have defined supportive care as any disease- or treatment-related condition experienced by children with cancer, excluding psychosocial conditions, palliative care, survivorship, or procedural topics). To address this gap, we conducted a consensus-building exercise among global experts to define and prioritize topics for supportive care.
View Article and Find Full Text PDFOnconephrology, an emerging discipline nestled at the intersection of nephrology and oncology, has experienced remarkable growth over the past 15 years. This evolution has been punctuated by pivotal events, including establishing the American Society of Onconephrology, dedicated forums, and journals, highlighting its increasing significance. The clinical landscape of onconephrology is diverse, encompassing AKI in patients with cancer, toxicity from anticancer treatments, and a spectrum of electrolyte disorders, necessitating close collaboration between nephrologists and oncologists.
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