Publications by authors named "M Fekih"
Primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH) are distinct liver diseases. Cases combining PBC and PSC, are extremely rare. Here, we present a case of a 39-year-old woman with a history of colonic Crohn's disease treated with azathioprine.
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- TNF alpha blockers like infliximab (IFX) and adalimumab (ADA) are effective for inflammatory diseases but about 30% of patients don't respond, possibly due to anti-drug antibodies (ADAbs).
- A study involving 197 patients found that 40% of those on IFX and 25% on ADA tested positive for ADAbs, with varying rates across conditions (RA, SpA, and CD).
- Despite the presence of ADAbs being linked to lower drug levels, they did not correlate with disease activity, suggesting that other factors besides immunogenicity may influence treatment failures.
Isoniazid (INH), being the first-line drug used as an anti-tuberculosis drug, is known to be associated with physiological deteriorations including hepatic and neurologic disturbances. This study was aimed at biochemical and behavioral characterization of toxic manifestations of isoniazid treatment in rats. Experimental animals were divided into four groups.
View Article and Find Full Text PDFOffice hysteroscopy before first in vitro fertilization. A randomized controlled trial.
J Gynecol Obstet Hum Reprod
September 2021
Background: Implantation failure remains a mystery since decades. This procedure needs a "top quality embryo" and a "normal" uterine cavity. To assess uterine cavity before first in vitro fertilization (IVF), many diagnostic tools could be used.
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