Background Objectives: Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic disease and significant health concern particularly in endemic regions. We aimed to evaluate the efficacy in dexamethasone treatment on clinical outcomes in CCHF patients.
Methods: We included adult patients diagnosed with CCHF and those whose platelet count dropped to 70,000/mm3 or lower.
Genomic repeat sequences are patterns of nucleic acids that exist in multiple copies throughout the genome. More than 60 Mendelian disorders are caused by the expansion or contraction of these repeats. Various specific methods for determining tandem repeat variations have been developed.
View Article and Find Full Text PDFBackground: Ocrelizumab (OCR) effectively modifies the disease course in multiple sclerosis (MS) patients but may cause a preinfusion "wearing-off phenomenon" (WoP). This study explored the prevalence, timing, and severity of this phenomenon in MS patients using the OCR, as well as the associated symptoms and treatment satisfaction.
Methods: We conducted a prospective multicenter study across 11 MS centers involving MS patients aged 18-70 years who had received at least two OCR doses.
Mining is one of the most risky and dangerous sectors. It is impossible to ignore the losses of life and material experienced by occupational accidents, which take place in the field of mining. Risk analysis begins with a risk assessment to identify the probability and severity of workplace hazards.
View Article and Find Full Text PDF