Publications by authors named "M Fastiggi"
Purpose: To analyze the referral patterns and the clinical and therapeutic features of patients diagnosed with uveitis in an Italian tertiary referral center to provide a comparison with previously published series from the same center.
Methods: Retrospective retrieval of data on all new referrals to the Ocular Immunology Unit in Reggio Emilia (Italy) between November 2015 and April 2022 and comparison with previously published series from the same center.
Results: Among the 1557 patients, the male-to-female ratio was 1:1.
Article Synopsis
- - Uveitis is rare in children and hard to diagnose and treat, with few studies available on its epidemiology in this age group and limited data from developed countries.
- - Anterior uveitis is the most common form globally, particularly in Western regions where juvenile idiopathic arthritis is prevalent, while intermediate uveitis often lacks links to systemic diseases.
- - In contrast, posterior uveitis and panuveitis are more common in low- and middle-income countries due to higher rates of infectious diseases and conditions like Behçet and Vogt-Koyanagi-Harada diseases, although improvements in diagnosis have led to a decrease in idiopathic uveitis cases.
Background: Euthyroid sick syndrome (ESS) is characterized by low serum levels of free triiodothyronine (fT3) with normal or low levels of thyroid stimulating hormone (TSH) and free thyroxine (fT4) and is reported in different acute clinical situations, such as sepsis, diabetic ketoacidosis and after cardiac surgery. Our aim was to evaluate the predicting role of ESS for disease severity in patients with Multisystem Inflammatory Syndrome in children (MIS-C).
Methods: A single-centre observational study on consecutive patients with MIS-C.
Background: Pyomyositis is an unusual bacterial infection but potential severe in children. Staphylococcus Aureus is the main caused of this disease (70-90%), following by Streptococcus Pyogenes (4-16%). Streptococcus Pneumoniae rarely caused invasive muscular infections.
View Article and Find Full Text PDFObjective: To evaluate the efficacy of levofolinic acid (LVF) administered 48 h before methotrexate (MTX) in reducing gastrointestinal side effects without interference with drug efficacy.
Methods: A prospective observational study was performed including patients with Juvenile Idiopathic Arthritis (JIA) reporting significant gastrointestinal discomfort after MTX despite taking a dose of LVF 48 h after MTX. Patients with anticipatory symptoms were excluded.