Publications by authors named "M Farley"

Article Synopsis
  • Extreme violence and psychological abuse in prostitution have severe impacts, with survivors often experiencing PTSD, depression, and dissociation, similar to torture survivors.
  • A study involving 45 women formerly in prostitution revealed high levels of torture experiences, including physical and sexual violence, and a strong need for comprehensive medical and psychological support.
  • Recognizing acts of torture within prostitution can help reduce survivor stigma and improve treatment approaches, advocating for a holistic care model akin to that used for state-sponsored torture victims.
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Pre-clinical murine and in vitro models have demonstrated that exercise suppresses tumour and cancer cell growth. These anti-oncogenic effects of exercise were associated with the exercise-mediated release of myokines such as interleukin (IL)-15. However, no study has quantified the acute IL-15 response in human cancer survivors, and whether physiological adaptations to exercise training (i.

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Article Synopsis
  • Reliable pQCT assessment is crucial for accurately tracking changes in bone and muscle quality over time, but its reliability across different days and age groups hasn't been fully explored.
  • *The study involved 72-86 participants (both men and women) aged 18-85, who completed two days of pQCT testing to measure the accuracy of bone, muscle area, and fat metrics.
  • *Most measurements showed good to excellent reliability, but muscle density showed poorer reliability in certain areas, with older adults experiencing increased biological error, particularly in forearm muscle density.
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A streamlined LC-MS/MS method utilizing protein precipitation and filtration extraction was developed to consolidate analyses for drug-facilitated crime (DFC), postmortem investigations, and driving under the influence of drugs (DUID) testing. Fifty-seven target drug and metabolite analytes eluted in under 6-minutes and compromised of GHB precursors (1), hallucinogens (3), muscle relaxants (3), anticonvulsants (7), antidepressants (20), antihistamines (5), antipsychotics (11), antihypertensives and alpha-adrenergics (3), analgesics and anesthetics (3), and miscellaneous (1) in blood (quantitatively) and urine (qualitatively). Limits of detection were set to meet the more challenging sensitivity requirements for DFC, and are therefore also suitable for postmortem investigations, and other forensic casework, including DUID.

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