Distributive and Refractory Shock in Myxoedema Coma.

Myxoedema coma is a rare medical emergency, presenting even less commonly without sepsis and with the diagnosis of distributive shock. Reports of catecholamine-refractory shock are scarce. This report describes the case of a 54-year-old male, who presented to the emergency department with altered mental status.

Gut Neuropathies and Intestinal Motility Disorders.

Background: The enteric nervous system plays a key role in the coordination of gastrointestinal motility together with sympathetic, parasympathetic, and extrinsic sensory pathways. In some cases, abnormalities in neural activity in these pathways contribute to disorders of gut motility. Where this is associated with damage or death of enteric neurons, usually detected by microscopy, this is considered a gut neuropathy.

Caffeine Responsiveness Before and After Pilates Training in Healthy Older Adults.

Objective: The study aimed to assess responsiveness to the effects of acute caffeine intake after 8 weeks of Pilates intervention in healthy older adults.

Methods: Fifteen healthy older adults performed physical performance regarding daily practice, strength, and balance tests after ingestion of acute 5 mg/kg of caffeine or placebo before and after Pilates training.

Results: The caffeine intake reduced, regardless of Pilates training, the time in 10-m walk test (before placebo vs caffeine, 6.

Embryoscopy and targeted embryo biopsy for the management of early abortion.

Purpose: To evaluate the safety, accuracy, and effectiveness of embryoscopy for the management of early abortion and to test the hypothesis that targeted embryo and chorionic villi sampling avoids maternal cell contamination (MCC) for genetic testing of products of conception (POC).

Methods: This ambispective study included 74 consecutive patients presenting with early abortion. Gestations between 5 and 9 weeks, obtained either spontaneously or through assisted reproductive technologies were included.