Rapid identification and phenotyping of nonalcoholic fatty liver disease patients using a machine-based approach in diverse healthcare systems.

Nonalcoholic fatty liver disease (NAFLD) is the most common global cause of chronic liver disease and remains under-recognized within healthcare systems. Therapeutic interventions are rapidly advancing for its inflammatory phenotype, nonalcoholic steatohepatitis (NASH) at all stages of disease. Diagnosis codes alone fail to recognize and stratify at-risk patients accurately.

Prediction of new-onset atrial fibrillation in patients with hypertrophic cardiomyopathy using machine learning.

Aims: Atrial fibrillation (AF) is the most common sustained arrhythmia among patients with hypertrophic cardiomyopathy (HCM), leading to increased symptom burden and risk of thromboembolism. The HCM-AF score was developed to predict new-onset AF in patients with HCM, though sensitivity and specificity of this conventional tool are limited. Thus, there is a need for more accurate tools to predict new-onset AF in HCM.

Influence of zonular tension on molecular transport in the porcine ocular lens.

Introduction: Accommodation is the process of changing the ocular lens' refractive power and focal distance. This process involves application of biomechanical forces on the lens by the surrounding musculature. Previous studies have demonstrated that the lens epithelium demonstrates mechanotransduction and that tension influences its chemical activity.

Comment on Drozdowska-Szymczak et al. Incidence and Risk Factors of Cholestasis in Newborns with Hemolytic Disease-A Case-Control Study. 2024, , 3190.

We read with interest the recently published article in the , by Drozdowska-Szymczak et al [...

Weight loss, nutritional aspects and quality of life in head and neck cancer survivors.

Objectives: Comprehensive care is fundamental to cancer survivors enduring long-term side-effects of cancer treatment including nutrition impact symptoms and critical weight loss (CWL). The aim of our study was to address weight loss (WL), nutritional aspects, and quality of life (QoL) in head and neck cancer (HNC) survivors.

Study Design: This was a cross-sectional study of HNC patients treated at the Sapienza University-Hospital, 2018-2022.