Publications by authors named "M F Maciel"

This study aimed to investigate the impact of adding aroeira leaf extract (Schinus terebinthifolius Raddi) to a yam starch film matrix, focusing on the development of potentially active films and the evaluation of their physicochemical, mechanical, optical, and antioxidant properties. Films were produced using the casting method with varying extract concentrations (0, 3, 6, 12, and 15 %), yam starch (2 %), and glycerol (1 %). The antioxidant properties were analyzed by determining the total phenolic content, 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) radical scavenging, ferric reducing power, and 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical elimination, which revealed a significant increase in antioxidant properties as the extract concentration increased.

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In the pursuit of personalized medicine, there is a growing demand for computational models with parameters that are easily obtainable to accelerate the development of potential solutions. Blood tests, owing to their affordability, accessibility, and routine use in healthcare, offer valuable biomarkers for assessing hemostatic balance in thrombotic and bleeding disorders. Incorporating these biomarkers into computational models of blood coagulation is crucial for creating patient-specific models, which allow for the analysis of the influence of these biomarkers on clot formation.

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Probiotics are microorganisms that provide health benefits at adequate doses and exhibit notable antioxidant and antimicrobial activities. These properties play crucial roles in combating chronic diseases linked to oxidative stress and antimicrobial resistance. This review aimed to summarize the antioxidant and antimicrobial properties of probiotics determined in in vitro studies and discuss mechanistic actions and analysis methods.

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Article Synopsis
  • Infections from the dengue virus, Orthoflavivirus denguei, can show no symptoms or a range of clinical signs due to its complex interactions with viral and host factors.
  • The study examined specific genetic variations (SNPs) in the interleukin-10 (IL-10) gene among 333 individuals in northeastern Brazil to see how they relate to symptomatic dengue.
  • Findings revealed that certain genotypes and the G allele of the -1082 A/G SNP are associated with a higher risk of developing symptomatic dengue, particularly in contrast to those with asymptomatic infections.
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