Publications by authors named "M F Lima-Costa"
To investigate the elements of the social network associated with frailty syndrome in older Brazilian adults. Baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil, 2015-2016) were used. Frailty was defined by the Fried phenotype (unintentional weight loss, exhaustion, weakness, slowness, and low level of physical activity).
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- - The study aimed to explore how family characteristics, like having a partner or children, affect loneliness in Brazilians aged 50 and older, considering both the presence and severity of loneliness.
- - Data was collected from over 7,000 participants in a national aging study, using a specific loneliness scale to measure loneliness alongside family dynamics such as marital status and living arrangements.
- - Findings showed that family relationships with partners significantly impacted loneliness levels, with those cohabiting reporting lower loneliness; results suggest that enhancing social support for older adults with smaller family units is important.
Female Reproductive Period Length, Parity and Hormonal Replacement Therapy and Dementia: The Elsi-Brazil Study.
Int J Geriatr Psychiatry
November 2024
Introduction: Alzheimer's disease and other dementia have a higher incidence among women and that risk factors specific to the female sex could be involved. Few studies looked into female reproductive factors and their association with dementia in low-and middle-income countries.
Materials And Methods: We analyzed the baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil) and included data from 2594 women aged 60 years and older.
Article Synopsis
- Latin Americans are often overlooked in genetic studies, which can widen gaps in personalized medicine due to the challenges of accessing genetic data and consent processes.
- The Genetics of Latin American Diversity (GLAD) Project compiles genetic information from over 53,000 individuals across various regions to explore diverse ancestry and gene flow in the Americas.
- GLAD includes a tool called GLAD-match to align external genetic samples with its database while protecting individual privacy, thus supporting more inclusive genomic research and enhancing personalized medicine for Latin Americans.
Article Synopsis
- The study investigates how cardiometabolic multimorbidity (CMM) and depression affect cognitive function in older adults, aiming to understand their individual and combined impacts.
- It harmonizes data from 14 international cohort studies and utilizes various scales to assess CMM and depression among participants who did not have dementia at the start of the study.
- Findings include the analysis of over 30,000 older adults, revealing that both CMM and depression are linked to cognitive decline, with further validation through additional studies across different settings.