Publications by authors named "M F Leconte des Floris"
Cisplatin is a nephrotoxic agent able to damage renal function both in acute and chronic phases. Radiotherapy concomitant with cisplatin 100 mg/m given once every 3 weeks is the curative standard of care for locally advanced head and neck cancer. A prospective evaluation of a wide range of biochemical and anthropometrical parameters, handgrip strength, risk of malnutrition, visual analogue scale of appetite, and body composition was performed before, during, and after concomitant chemoradiotherapy in 60 consecutive patients affected by locally advanced head and neck cancer.
View Article and Find Full Text PDFBackground: Antibody-mediated rejection is a significant cause of kidney transplant failure. Recent studies have shown that the MHC class I gene influences the transplantation outcome. However, the role of the primary receptor, NKG2D, has yet to be explored.
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- * The research analyzed data from 465 kidney cancer patients and 256 living kidney donors, revealing high rates of post-surgery AKI, especially among donors, and varied progression of CKD depending on the type of surgery performed.
- * Findings indicated that factors such as age and health conditions prior to surgery can predict CKD progression, emphasizing that both kidney cancer patients and living donors face considerable risks related to kidney function after surgery.
Article Synopsis
- Multiple sclerosis (MS) is an autoimmune disease linked to both genetic and environmental factors, involving the immune system and myelin changes associated with RNA, particularly circular RNAs (circRNAs).
- A study analyzed circRNA expressions in peripheral blood mononuclear cells (PBMCs) from five newly diagnosed MS patients and five healthy controls, using a microarray to identify significant differences.
- The research found 64 differentially expressed circRNAs, with 53 downregulated in MS patients, validated in a larger cohort, suggesting a specific circRNA as a potential biomarker for MS severity and progression.
This retrospective analysis investigates the outcomes and complications of 682 kidney biopsies performed at ARNAS G. Brotzu from 2010 to 2021. Our findings indicate a minor complication rate of 9.
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