[Comparative study of psychometric results of 2 french speaking populations with hypothyroidism detected at birth].

The authors compare the data from the psychological assessment of a cohort of 191 French speaking hypothyroid children detected by neonatal screening: 99 were followed in Quebec and 92 in Lille, according to two independent programs. Three age levels were selected: 12-18 months, 5 and 7 years. Data were similar and, in both studies, results of the later ages were slightly lower than the norms of the tests or results obtained in control groups.

[Growth and bone maturity during congenital hypothyroidism screened in the neonatal period. Apropos of 82 cases].

Systematic neonatal screening of congenital hypothyroidism (CH) allowed to detect 82 children (62 girls and 20 boys) including 73% with ectopic thyroid, 18% with athyreosis and 9% with eutopic thyroid. They were followed for 1 to 7 years according to the same protocol. Skeletal maturity was studied according to 2 methods: TW2 and Sempé's numerical.

[Prognostic value of bone surface in hypothyroidism detected in neonatal period].

Bone maturation at the time of diagnosis has been considered as a prognostic factor of congenital hypothyroidism. Using bone area as an index of bone maturation, we have compared the psycho-intellectual outcome of infants with high bone area (group I) at time of diagnosis, with those with low area (group II), in a population of infants with congenital hypothyroidism detected by a neonatal screening program. We found that children from group I had better performances than those from group II whatever the age of the evaluation (1, 2, 5 or 7 years).

[West's syndrome. A clinical, therapeutic and prognostic study. Apropos of 66 cases].

The charts of 66 children suffering from West syndrome followed by the paediatric department of the University Central Hospital, Lille, between 1957 and 1984 were reviewed: 24 cases were followed for more than 10 years; 20 cases from 5 to 10 years; 22 cases from 1 to 5 years. Age at onset of the disease ranged from 3 to 5 months (37.8%) and 6 to 8 months (30.