Publications by authors named "M F Housset"
The coordinated spatial arrangement of organelles within a tissue plane, known as planar cell polarity (PCP), is critical for organ development and function. Gradients of morphogens and their receptors typically set-up PCP, but whether non-molecular cues, akin to phototropism in plants, also play a part remains unknown. Here, we report that basal bodies of newborn photoreceptor cells in the mouse retina are positioned centrally on the apical surface but then move laterally during the first postnatal week, generating cell-intrinsic asymmetry in the retinal plane.
View Article and Find Full Text PDFBackground: Primary plantar hyperhidrosis has a severe impact on quality of life and conservative treatments are only effective in the short term. Thoracic sympathectomy has proven its effectiveness in the treatment of palmar hyperhidrosis, but lumbar sympathectomy for plantar hyperhidrosis remains poorly described.
Objectives: To report the satisfaction of patients with primary plantar hyperhidrosis treated with mechanical lumbar sympathectomy as well as their postoperative complications.
Introduction: Bladder cancer occurs mainly in older adults and surgery is not always possible when there are geriatric conditions and comorbidities. Trimodal treatment (TMT) combining trans-urethral resection of bladder tumour (TURBT) followed by concurrent chemoradiation (CRT) would be a curative alternative in such patients.
Materials And Methods: All consecutive patients 75 years of age and older with non-metastatic muscle-invasive bladder cancer (MIBC) treated with TMT by Georges Pompidou European Hospital team were retrospectively analysed.
Article Synopsis
- The study investigates a three-part conservative treatment approach (trimodal therapy) for patients with muscle-invasive bladder cancer who are operable, suggesting it as an alternative to radical surgery.
- Involving transurethral resection followed by radiochemotherapy, the treatment resulted in an 83% histologic response rate after therapy, with acceptable long-term outcomes regarding cancer recurrence and bladder preservation.
- The findings indicate that this conservative strategy should be considered for appropriately selected patients, as it showed promising functional and oncological results with limited side effects.