Randomized controlled effect of treadmill walking exercise on liver enzymes, psychological burden, and erectile dysfunction in men with hepatitis C.

Introduction: Exercise is a simple, safe, and affordable solution that can be easily taught to men with chronic illnesses to improve their psychological burden and sexual health.

Aim: Since the role of exercise in ameliorating the psychological burden associated with erectile dysfunction (ED) in hepatitis C (HC) men was not explored, this research aimed to explore this role.

Material And Methods: This HC study was a randomized-controlled exercise-rehabilitation trial.

Do oxidized low-density lipoproteins link to extra hepatic manifestations in chronic, non-cirrhotic HCV patients?

Background: Tissue damage by viral hepatitis is a major cause of morbidity and mortality worldwide. Oxidation reactions and reactive oxygen species (ROS) transform proteins and lipids in plasma low-density lipoproteins (LDL) into the abnormal oxidized LDL (ox-LDL). Hepatitis C virus (HCV) infection induces oxidative/nitrosative stress from multiple sources, including the inducible nitric oxide synthase (iNOS), the mitochondrial electron transport chain, hepatocyte NAD(P)H oxidases (NOX enzymes), and inflammation.

Ecological multivariate assisted spectrophotometric methods for determination of antipyrine and benzocaine HCl in presence of antipyrine official impurity and benzocaine HCl degradant: toward greenness and whiteness.

A simple and green chemometrics-assisted spectrophotometric technique has beendeveloped and validated for the determination of antipyrine (ANT) and benzocaine HCl (BEN) along with the official impurity of ANT, antipyrine impurity A (ANT imp-A), and the degradation product of BEN, p-amino benzoic acid (PABA), in their quaternary mixture. Three models were developed and compared: partial least squares (PLS), artificial neural networks (ANN), and multivariate curve resolution-alternating least squares (MCR-ALS) where the four studied drugs were successfully quantified. The quantitative determination of the studied drugs was assessed using percentage recoveries, standard errors of prediction, and root mean square errors of prediction.

A new cadinane-type sesquiterpenoid glucoside from .

A new cadinane-type sesquiterpene glucoside, 10-hydroxy, 1(H), 6(H), 7(H), 8(H)-cadinane-4-en-8-O--D-glucoside () as well as, 2 known analogues [sinaicin ()- linichlorinA ()], were isolated from the CHCl:MeOH organic extract of . Chemical structures of all isolated compounds were established depending upon the spectroscopic data including, 1D and 2D NMR and HRMS. Colo-205 (colorectal cancer), HepG2 (hepatocellular carcinoma) and MCF-7 (breast adenocarcinoma) and cancer cell lines were used to test the cytotoxic potential of the isolated compounds (-).

Synthesis of eco-friendly lipid-magnetite nanocomposite encapsulated Poinciana extract as promising insecticide against Culex pipiens.

Mosquito-borne diseases represent a growing health challenge over time. Nanostructured lipid carriers (NLCs) are the second generation of solid lipid nanoparticles (SLNs), and they continue to attract significant interest as potential diagnostic and therapeutic tools in disease inhibition and insect control. Activated ingredients presented in the Poinciana leaves were extracted and GC-MS data indicated an increased abundance of terpenes, flavonoids, and phenolic substances.