Passive treatment of acid mine drainage from the Sidi-Kamber mine wastes (Mediterranean coastline, Algeria) using neighbouring phosphate material from the Djebel Onk mine.

Passive abiotic treatment of acid mine drainage (AMD) was investigated using phosphate mining residuals (raw low-grade phosphate ore, phosphatic limestone wastes, and phosphate mine tailings) from the Djebel Onk mine, Algeria. Laboratory batch tests were performed using the main expected lithologies of phosphate materials in contact with synthetic AMD, which had a low pH (3.08) and contained high concentrations of Fe (600 mg/L), Mn (40 mg/L), Mg (10 mg/L), Zn (20 mg/L), Cu (25 mg/L), As (50 mg/L), and sulfate (3700 mg/L).

Hyperpolarized C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma.

Glioblastoma (GBM) is the most aggressive brain tumor type in adults. GBM is heterogeneous, with a compact core lesion surrounded by an invasive tumor front. This front is highly relevant for tumor recurrence but is generally non-detectable using standard imaging techniques.

In vivo characterization of brain metabolism by H MRS, C MRS and FDG PET reveals significant glucose oxidation of invasively growing glioma cells.

Glioblastoma are notorious for their highly invasive growth, diffusely infiltrating adjacent brain structures that precludes complete resection, and is a major obstacle for cure. To characterize this "invisible" tumor part, we designed a high resolution multimodal imaging approach assessing in vivo the metabolism of invasively growing glioma xenografts in the mouse brain. Animals were subjected longitudinally to magnetic resonance imaging (MRI) and H spectroscopy (MRS) at ultra high field (14.

Immunological and inflammatory mapping of vascularized composite allograft rejection processes in a rat model.

Background: Hand and face vascularized composite allotransplantation (VCA) is an evolving and challenging field with great opportunities. During VCA, massive surgical damage is inflicted on both donor and recipient tissues, which may contribute to the high VCA rejection rates. To segregate between the damage-induced and rejection phase of post-VCA responses, we compared responses occurring up to 5 days following syngeneic versus allogeneic vascularized groin flap transplantations, culminating in transplant acceptance or rejection, respectively.