Developing Topics.

Background: People with young-onset Alzheimer`s disease (YOAD) is a diagnosis given when the neurocognitive process begins before the age of 65 and often presents more global impairments, and the course of the disease is faster. In contrast, in late-onset (LOAD), the most prominent loss occurs in short-term memory. Therefore, the age at onset of the disease may affect global functioning in different ways.

Developing Topics.

Background: Social Cognition (SC) is the ability to recognize and understand socially relevant stimuli, which contributes to an adequate social decision. Different neurological conditions may affect this cognitive domain, especially Alzheimer's disease (AD). SC impairments are commonly associated with the progression of the disease and contribute to the dependence of people with AD, influencing their functional disability and the burden on family members and caregivers.

Developing Topics.

Background: The progression of dementia may be followed by decreased sexual activity for People with Alzheimer's Disease (PwAD) and their spouse-carers. We designed this study to investigate the perception of change in sexual activity and sexual satisfaction among couples whose spouses were diagnosed with Alzheimer's Disease (AD).

Method: Using a cross-sectional design, we compared 74 dyads of people with Alzheimer´s disease (PwAD) and their spouse-carers, and 21 elderly dyads control.

Use of Virtual Reality Glasses During Healthcare: An Integrative Review.

Integrating technology into healthcare services has direct implications for the efficacy and performance of client care. In view of this, the aim was to identify the possibilities of using virtual reality glasses in healthcare. An integrative literature review was conducted in October 2024, searching in MEDLINE, LILACS, BDENF, Scopus, Web of Science, EMBASE, and Science Direct.

Differential Neutralization Profiles of 17DD Vaccinated Population to 17D-204 and 17DD Vaccine Strains.

: Yellow fever virus (YFV) (, ) is the etiologic agent of yellow fever (YF), a vector-borne disease with significant morbidity and mortality across the tropics and neotropics, despite having a highly efficacious and safe vaccine (17D). Vaccination provides lifelong protection from YF disease mediated by humoral immunity. There are several versions of the original 17D vaccine: 17D-204 (marketed in the USA as YF-VAX, in France as Stamaril, and in China as Tiantan-V), 17D-213 (Russian Federation), and 17DD (by FIOCRUZ in Brazil).