Publications by authors named "M F Carlier"

Background: Recurrent infections of the nose, sinuses and ears are common problems for people with primary ciliary dyskinesia. While pulmonary exacerbations in primary ciliary dyskinesia are defined, there is no definition for ear-nose-throat exacerbations, a potential outcome for research and clinical trials.

Methods: We set up an expert panel of 24 ear-nose-throat specialists, respiratory physicians, other healthcare professionals and patients to develop consensus definitions of sinonasal and otological exacerbations in children and adults with primary ciliary dyskinesia for research settings.

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  • * Symptoms typically develop hours to days following the trauma or after procedures like bone reduction.
  • * MRI scans can reveal diffuse neurological damage, and in this case, symptoms emerged in the recovery ward with a complete blockage in the left middle cerebral artery due to fat particles.
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  • PMT compounds, such as certain fungicides and herbicides, are concerning because they can pollute drinking water due to their persistence and high solubility in water.
  • The study focused on 36 compounds, including triazoles and PFAS, assessing their effects on key hormone receptors and hormone production through specific lab assays.
  • Findings indicated that several triazoles and triazine herbicides can disrupt hormone function, supporting previous research on their endocrine-disrupting properties and highlighting the need for further investigation and regulatory measures.
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  • The French National Authority for Health (HAS) has released new guidelines for patient blood management (PBM) during surgeries, focusing on three key areas: optimizing red blood cell count, minimizing blood loss, and managing anemia tolerance.
  • Preoperative recommendations include identifying anemia and iron deficiency early, especially for surgeries with a higher risk of bleeding.
  • Intraoperative strategies involve using tranexamic acid and certain surgical techniques to control bleeding, while postoperative guidance emphasizes reducing blood sampling and monitoring for anemia to determine if treatments like intravenous iron are needed.
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