Publications by authors named "M F Breslin"

Importance: Fracture-related infection (FRI) is a serious complication following fracture fixation surgery. Current treatment of FRIs entails debridement and 6 weeks of intravenous (IV) antibiotics. Lab data and retrospective clinical studies support use of oral antibiotics, which are less expensive and may have fewer complications than IV antibiotics.

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Voltage-gated sodium (Nav) channels present untapped therapeutic value for better and safer pain medications. The Nav1.8 channel isoform is of particular interest because of its location on peripheral pain fibers and demonstrated role in rodent preclinical pain and neurophysiological assays.

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Purpose: Posttraumatic stress disorder (PTSD) is prevalent and is associated with protracted recovery and worse outcomes after injury. This study compared PTSD prevalence using the PTSD checklist for DSM-5 (PCL-5) with the prevalence of PTSD risk using the Injured Trauma Survivor Screen (ITSS).

Methods: Adult trauma patients at a level I trauma center were screened with the PCL-5 (sample 1) at follow-up visits or using the ITSS as inpatients (sample 2).

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Article Synopsis
  • The study examined how interpersonal violence and the use of trauma recovery services changed during the COVID-19 pandemic at an urban trauma center.
  • A total of 1,908 crime victims were analyzed, revealing a significant increase in victims presenting after the national emergency declaration, with a 74.6% rise in monthly cases.
  • Despite the increase in violence, engagement with trauma recovery services significantly declined, with patients having fewer interactions and shorter hospital stays post-COVID-19 compared to before the pandemic.
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