Publications by authors named "M F Bellamy"

Background & Aims: Therapeutic plasma exchange (PEX) has shown potential in improving transplant-free survival in acute liver failure (ALF) however the mechanism of action is not understood. This exploratory study aimed to elucidate the circulating proteomic changes associated with PEX in ALF to provide insight into mechanisms underlying the benefit of this therapy.

Methods: Consecutive patients admitted with ALF between June 2019 and August 2020 were enrolled.

View Article and Find Full Text PDF
Article Synopsis
  • The Million Person Study (MPS) investigates the health impacts of gradual exposure to ionizing radiation on over one million U.S. radiation workers and veterans, focusing on both cancer and non-cancer conditions.
  • Recent efforts have highlighted mortality patterns related to neurological and behavioral disorders, such as Parkinson's and Alzheimer's diseases, by analyzing claims data from Medicare beneficiaries.
  • To manage the extensive and complex dataset, the MPS is developing specialized open-source software (Colossus) to facilitate detailed evaluation of health outcomes and related factors from the collected health information.
View Article and Find Full Text PDF

Introduction: Mechanical ventilation (MV) is a common and often live-saving intervention on the Intensive Care Unit (ICU). The optimisation of sedation to mechanical ventilation is fundamental, and inappropriate sedation has been associated with worse outcomes. This scoping review has been designed to answer the question '

Methods: The protocol was designed using the PRISMA-ScR checklist and the JBI manual for evidence synthesis.

View Article and Find Full Text PDF

Objective: This follow-up study of uranium processing workers at the Fernald Feed Materials Production Center examines the relationship between radiation exposure and cancer and non-cancer mortality among 6403 workers employed for at least 30 days between 1951 and 1985.

Methods: We estimated cumulative, individual, annualised doses to 15 organs/tissues from external, internal and radon exposures. Vital status and cause of death were ascertained in 2017.

View Article and Find Full Text PDF