Optimization of extraction in supercritical fluids in obtaining seed oil by response surface methodology and artificial neuronal network coupled with a genetic algorithm.

When processing lucuma (), waste such as shells and seeds is generated, which is a source of bioactive compounds. Recently, lucuma seed (LS), especially its oily fraction, has been studied for containing phytosterols and tocopherols, powerful antioxidants with health benefits. This study proposes lucuma seed oil (LSO) extraction using supercritical fluid (SCF) to improve the quality of the extract and minimize the environmental impact.

Multimodal evaluation of osteosarcoma choroidal metastasis.

Background: Osteosarcoma (OS) is the most common primary bone carcinoma. Adulthood most frequent intraocular malignant tumor is choroidal metastasis; however, these are rarely related to sarcomas. There are only two OS-related choroidal metastasis cases reported in the literature, both prior to 1970.

Ophthalmic genetics in South America.

South America comprises of heterogeneous topographies, populations, and health care systems. Therefore, it is not surprising to see differences among the countries regarding expertise, education, and practices of ophthalmic genetics for patients with rare eye diseases. Nevertheless, common challenges such as limited genetics training in medical schools and among ophthalmologists, scarcity of diagnostic tools for phenotyping, and expensive genetic testing not covered by the public healthcare systems, are seen in all of them.

Dispersion tailoring in wedge microcavities for Kerr comb generation.

The shaping of group velocity dispersion in microresonators is an important component in the generation of wideband optical frequency combs. Small resonators-with tight bending radii-offer the large free-spectral range desirable for wide comb formation. However, the tighter bending usually limits comb formation as it enhances normal group velocity dispersion.