Fluid structure interaction with contact surface methodology for evaluation of endovascular carotid implants for drug-resistant hypertension treatment.

Drug-resistant hypertensive patients may be treated by mechanical stimulation of stretch-sensitive baroreceptors located in the sinus of carotid arteries. To evaluate the efficacy of endovascular devices to stretch the carotid sinus such that the induced strain might trigger baroreceptors to increase action potential firing rate and thereby reduce systemic blood pressure, numerical simulations were conducted of devices deployed in subject-specific carotid models. Two models were chosen--a typical physiologic carotid and a diminutive atypical physiologic model representing a clinically worst case scenario--to evaluate the effects of device deployment in normal and extreme cases, respectively.

Magnetoresistance oscillations of superconducting Al-film cylinders covering InAs nanowires below the quantum critical point.

When odd multiples of half flux quanta thread a cylindrical superconducting shell with a diameter d shorter than the zero temperature coherence length ξ(0), superconductivity is predicted to be destroyed. We show here that as d is reduced in comparison to ξ(0) the resistance attains the normal state value, which seems to be temperature independent in the vicinity of half flux quanta. The data are in agreement with recent theoretical results.