Confirmation of drug allergy in a general pediatrics outpatient clinic.

Background: Studies including diagnostic workups on true drug allergy in children are limited.

Objective: To evaluate the frequency of confirmed drug allergy in children with a history of suspected drug allergy who had applied to the general pediatric outpatient clinics of our hospital owing to various health problems.

Methods: The history of drug allergy was asked among children who applied to the general pediatric outpatient clinics of our hospital.

[Pollen food allergy syndrome].

Pollen food allergy syndrome, is a type I cross-reaction mediated by IgE antibodies between an aeroallergen and a plant-derived antigen. Main symptoms are typically consist of localized oral symptoms such as numbness of the lip or mouth, itching, tingling and swelling of lips, tongue, palate and pharynx without systemic symptoms. Patients with seasonal allergic rhinitis, asthma or both more frequently experience pollen food allergy syndrome.

Allergic and autoimmune disorders in families with selective IgA deficiency.

Background/aim: IgA deficiency is the most common human primary immunodeficiency. The prevalence of allergic disorders and autoimmunity is thought to be increased in selective IgA deficiency (sIgAD). However, it is currently unclear if these disorders coincide within these families.

Severe Cutaneous Adverse Drug Reactions in Pediatric Patients: A Multicenter Study.

Background: The severe cutaneous adverse drug reactions (SCARs) are rare but could be life-threatening. These include drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome, toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis.

Objective: The purpose of this study was the evaluation of the clinical characteristics of patients with the diagnosis of SCARs.

Clinical and etiologic evaluation of the children with chronic urticaria.

Background: Chronic urticaria (CU) is a skin disorder defined as daily or almost daily exhibition of pruritic and transient wheals that last for 6 weeks. CU is divided into two subtypes: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU).

Objectives: To evaluate the clinical features, possible causes, associated findings, and laboratory results of different subtypes of CU in children according to a new classification.