Posterior interosseous artery distal ulna graft for management of radius nonunion: Technique and case report.

Distal radius fracture nonunion can result in significant deformity, loss of function, and chronic pain. Presented here is a case of distal radius nonunion that was surgically reconstructed with a pedicled distal ulna bone graft based on the periosteal branches of the posterior interosseus artery (PIA). This technique has limited prior utilization for adult distal radius nonunion treatment but offers an effective option for surgical reconstruction of distal radius nonunion with preservation of the radiocarpal joint, utilizing a less invasive surgery that also reduces hospitalization stay.

The coronavirus nsp14 exoribonuclease interface with the cofactor nsp10 is essential for efficient virus replication and enzymatic activity.

Coronaviruses (CoVs) encode non-structural proteins (nsp's) 1-16, which assemble to form replication-transcription complexes that function in viral RNA synthesis. All CoVs encode a proofreading 3'-5' exoribonuclease in non-structural protein 14 (nsp14-ExoN) that mediates proofreading and high-fidelity replication and is critical for other roles in replication and pathogenesis. The enzymatic activity of nsp14-ExoN is enhanced in the presence of the cofactor nsp10.

State-Level Helmet Use Laws, Helmet Use, and Head Injuries in EMS Patients Involved in Motorcycle Collisions.

Objectives: Motorcycle helmets save lives and reduce serious injury after motorcycle collisions (MCC). In 2022, 18 states had laws requiring helmet use by motorcyclists aged ≥21 years. Our objective was to compare helmet use and head trauma in emergency medical services (EMS) patients involved in MCC in states with and without helmet use laws.

The effect of training distribution, duration, and volume on VO and performance in trained cyclists: A systematic review, multilevel meta-analysis, and multivariate meta-regression.

Objective: This study aimed to systematically investigate whether polarized or non-polarized training leads to greater physiological and performance adaptations in cyclists.

Design: A systematic review and meta-analysis were conducted, focusing on interventions categorized as polarized, non-polarized, or unclear. Inclusion criteria required participants to be at least recreationally trained cyclists (VO ≥ 59 ml/kg/min) and interventions lasting > 4 weeks.

Tissue Prior to the Initial Hematoxylin-Eosin Section Demonstrates Value as an Alternative Source of DNA for Molecular Testing.

Context.—: Small biopsies are used for histologic, immunophenotypic, cytogenetic, molecular genetic, and other ancillary studies. Occasionally, this diagnostic tissue is exhausted before molecular testing can be performed.