Publications by authors named "M Emond"
Background: T-cell-redirecting therapies, such as bispecific antibodies and chimeric antigen receptor T-cells, exploit the cytotoxic capabilities of the immune system to destroy cells expressing specific surface antigens, including malignant cells. These therapies have demonstrated unprecedented rates, depth, and duration of responses in relapsed and refractory multiple myeloma. However, there are significant challenges in implementing these therapies into practice, which require multidisciplinary and multicenter coordination and significant healthcare resources to effectively manage these patients.
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- The study aimed to assess how often older adults (65+) experience negative health outcomes during hospital stays after being treated for isolated hip fractures in emergency departments in Quebec.
- Involving 4,569 patients over a 14-year period, it found that 40% experienced at least one adverse event, with common issues including extended hospital stays, complications, and mortality.
- Key risk factors for these events included advanced age (over 75), male sex, cardiovascular disease, cognitive disorders, and multiple health conditions, while direct admission to surgery appeared to reduce risks.
Background: This study aims to evaluate the impact of Quebec's first hospital-at-home-inspired mobile Seniors' Clinic, the "Clinique des Ainés (CDA)", on frail older adults' returns to the Emergency Department (ED), mortality, and hospital Length Of Stay (LOS) and rehospitalizations.
Methods: Design: Quasi-experimental pre-post implementation cohort study.
Population: Patients aged ≥ 75 years admitted to the short-term geriatric unit after an ED consultation (control) or included by the CDA (intervention).
Article Synopsis
- Head injuries are the most common trauma cases in Emergency Departments, prompting a study in France to analyze the demographics and severity of these cases among adults visiting EDs.
- The study, involving 1,070 patients over three days, found that ground-level falls were the most frequent cause of head injuries, and most patients had either simple head trauma or mild traumatic brain injury (TBI).
- Results indicated that the median age of patients was 68.5 years, with a significant portion arriving at the ED within 2 hours of injury; however, the use of anticoagulants did not increase the risk of traumatic intracranial hemorrhage.
Background: We aimed to derive a clinical decision rule to identify patients with transient ischemic attack (TIA) or minor stroke most likely to benefit from echocardiography.
Methods: This multicentre prospective cohort study enrolled adults diagnosed with TIA/minor stroke in the emergency department who underwent echocardiograms within 90 days, from 13 Canadian academic emergency departments from October 2006 to May 2017. Our outcome was clinically significant echocardiogram findings.