The aim of this project is to fabricate fiber mats and hydrogel materials that constitute the two main components of a wound dressing material. The contributions of boric acid (BA) and zinc oxide (ZnO) to the physical and mechanical properties of polycaprolactone (PCL) is investigated. These materials are chosen for their antimicrobial and antifungal effects.
View Article and Find Full Text PDFBackground: Disruptive Mood Dysregulation Disorder (DMDD), characterized by severe irritability and temper outbursts, is a relatively new diagnosis included in the DSM-5. The study aimed to investigate the clinical characteristics, temperament, comorbidities, medication use, and sleep quality of children and adolescents diagnosed with DMDD and compare them with Major Depressive Disorder (MDD).
Methods: A total of 233 participants (DMDD: = 106; MDD: = 127) were assessed using the K-SADS-PL.
In this study, novel thiazole-chalcone analogs were synthesized, and their inhibitory effects on acetylcholinesterase (AChE) were examined. In vitro enzyme activity studies were conducted to calculate IC values, which were found to range between 2.55 and 72.
View Article and Find Full Text PDFIntroduction: It has been indicated that the thiol-disulfide homeostasis plays a role in the pathogenesis of COVID-19 infection. We assessed the impact on the thiol-disulfide homeostasis at 15-day intervals until 60 days, implicated in the pathogenesis of COVID-19, and its clinical relevance in disease progression.
Methods: In this study, 43 COVID-19 patients (18 females and 25 males) were categorized based on symptom severity, age group, and body mass index.