Effects of Scapular Angular Deviations on Potential for Rotator Cuff Tendon Mechanical Compression.

Background: One proposed mechanism of rotator cuff disease is scapular motion impairments contributing to rotator cuff compression and subsequent degeneration.

Purpose: To model the effects of scapular angular deviations on rotator cuff tendon proximity for subacromial and internal mechanical impingement risk during scapular plane abduction.

Study Design: Descriptive laboratory study.

A Peptide/MicroRNA-31 nanomedicine within an electrospun biomaterial designed to regenerate wounds in vivo.

microRNA-31 (miR-31) has been identified to be downregulated in pathologies associated with delayed wound repair. Thus, it was proposed that the delivery of a plasmid encoding miR-31 (pmiR-31) to the skin could hold potential in promoting wound healing. Effective delivery of pmiR-31 was potentiated by encapsulation with the CHAT peptide to form nanocomplexes, this improved cellular entry and elicited a potent increase in miR-31 expression in vitro in both skin human keratinocyte cell line (HaCaT) and human microvascular endothelial cell line (HMEC-1).

[Relationship between adaptation mechanisms and the level of functioning of the cardiovascular system in children with abnormalities of the large intestine and anorectal region].

The reserve potential of children with developmental defects of the large intestine and the anorectal area was assessed from cardiovascular function and its adaptation to the new level (determined from the vegetative tone) and adequacy of tissue perfusion. Forty-three children with the above disease, aged 2 months to 14 years, were examined. Three types of hemodynamic disorders were detected, corresponding to certain states of adaptation mechanisms.

Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4.

Insulin regulates essential pathways for growth, differentiation, and metabolism in vivo. We report a physiologically relevant system for dissecting the molecular mechanisms of insulin signal transduction related to glucose transport. This is an extension of our recently reported method for transfection of DNA into rat adipose cells in primary culture.