A comparison of the effect of two types of vibration exercise on the endocrine and musculoskeletal system.

Background: Whole body vibration (WBV) is a novel training intervention but a comparison of different methods of WBV has rarely been performed.

Aim: To compare the short and medium term effects of two regimens of WBV on endocrine status, muscle function and markers of bone turnover.

Patients And Methods: Over a period of 16 weeks, 10 men with a median age of 33 yrs (range, 29,49), were randomised to stand on the Galileo platform (GP) or Juvent1000 platform (JP) 3 times/wk.

Skeletal morbidity in children receiving chemotherapy for acute lymphoblastic leukemia and its association with mineral homeostasis and duration of inpatient stay.

Background: Reduced activity, older age, and abnormal bone mineral status are considered as important determinants of poor bone health in children with acute lymphoblastic leukemia (ALL). The independent contribution of these factors toward skeletal morbidity (SM) requires further investigation.

Aim: The aim of this study was to investigate the influence of activity, age, and mineral status over the first 12 months of chemotherapy on subsequent SM.

Skeletal morbidity in children receiving chemotherapy for acute lymphoblastic leukaemia.

Background: Children receiving chemotherapy for acute lymphoblastic leukaemia (ALL) may be susceptible to skeletal morbidity.

Aim: To determine the incidence and risk factors for skeletal morbidity in ALL children.

Patients And Methods: The medical records of all (n=186, boys=110) children presenting to a single centre with ALL between 1997 and 2007 and treated on UKALL97, UKALL97/01 or UKALL2003 were studied.

Secondary osteoporosis.

Secondary osteoporosis is more difficult to define in children than in adults but clearer definitions have recently been provided by the International Society for Clinical Densitometry. Whereas in adults, osteoporosis is defined on the basis of reduced bone density on scanning, in children the definition requires additional clinical parameters to be fulfilled. Secondary osteoporosis may arise either as a result of the effects of underlying disease or as a result of the treatment of such diseases (e.