Macromolecular interaction mechanism of the bacteriocin EntDD14 with the receptor binding domain (RBD) for the inhibition of SARS-CoV-2 and the JN.1 variant: Biomedical study based on elastic networks, stochastic Markov models, and macromolecular volumetric analysis.

Bacteriocins, a class of molecules produced by bacteria, exhibit potent antimicrobial properties, including antiviral activities. The urgent need for treatments against SARS-CoV-2 has proposed bacteriocins such as enterocin DD14 (EntDD14) as potential therapeutic agents. However, the mechanism of macromolecular interaction of EntDD14 for the inhibition of SARS-CoV-2 is not yet fully understood, and its efficacy against variants like JN.

How have the triplet pregnancies baseline characteristic and its outcomes changed over the last two decades?

Objective: Triplet pregnancies are high-risk pregnancies, and baseline characteristics and gestational care protocols have changed over years. The objective of this study is to compare the baseline characteristics and the prevalence of maternal, fetal, obstetric, and perinatal outcomes in triplet pregnancies between 2013 and 2024 (PII) and 2000 and 2012 (PI).

Methods: This is a single-center, observational retrospective case-control study that includes all triplet pregnancies followed up at the La Paz University Hospital between 2000 and 2024.

School-Based Eating Interventions-Are Students Eating Healthily?

School nutrition is an important key modifier in terms of child and adolescent nutrient intake [...

Psychometric Reliability to Assess the Perception of Women's Fulfillment of Maternity Rights.

The fulfillment of rights to maternal healthcare is a key factor for the wellbeing of women. However, there is a lack of an instrument to ascertain the experience of women during maternity to enable adequate monitoring. The aim of this study was to validate a new instrument to measure women's perception of the fulfillment of rights during healthcare in pregnancy and childbirth and immediately postpartum.