Publications by authors named "M El Abbes Faouzi"
Background: Osteogenesis imperfecta (OI) is a rare hereditary bone disease resulting from a defect in collagen synthesis or processing, leading to bone fragility, frequent fractures and skeletal deformities. OI is associated with increased respiratory morbidity and mortality, but the mechanisms of lung involvement are poorly understood, and there are no data on the natural history of lung function. We studied lung function over time in a cohort of adult OI patients at one center.
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- This study investigates the active compounds in Chenopodium ambrosioides for their analgesic and antidiabetic properties, motivated by the plant's therapeutic effects.
- The research utilized gas chromatography-mass spectrometry to analyze various aqueous extracts and fractions, finding several significant chemical families and compounds associated with these properties.
- In the assays, the ethyl acetate fraction (EAF) displayed the highest α-amylase inhibition, while the infused aqueous macerate (EAM) was the most effective against α-glucosidase, outperforming the standard antidiabetic drug acarbose.
A fast and sample cleanup approach for fluoxetine in human plasma was developed using protein precipitation coupled with LC-MS-MS. Samples were treated with methanol prior to LC-MS-MS analysis. Chromatographic separation was performed on a reverse phase column with an isocratic mobile phase of methanol and 10 mM ammonium formate pH acidified with formic acid (80:20, /) at a flow rate of 0.
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- Training primary care providers (PCPs) in a new method using a decision aid (DA) to promote smoking cessation did not lead to higher smoking abstinence rates after six months in smokers.
- The intervention increased quit attempts and the use of cessation aids in the short term, showing effectiveness in getting smokers to try quitting.
- Patients also felt more involved in their decision-making regarding smoking cessation when their PCPs used the DA approach, as indicated by higher scores on the CollaboRATE scale.
Background And Aim: Direct-acting antivirals (DAAs) have revolutionised the management of chronic hepatitis C. We analysed the use of different generations of DAAs over time in Switzerland and investigated factors predictive of treatment failure.
Methods: This retrospective study was conducted within the framework of the Swiss Association for the Study of the Liver and the Swiss Hepatitis C Cohort Study; it included all patients with chronic hepatitis C treated with DAAs between January 2015 and December 2019 at eight Swiss referral centres.