Publications by authors named "M Eiden"

Article Synopsis
  • Q fever (QF) and Rift Valley fever (RVF) are prevalent zoonotic diseases in Africa that pose health and economic challenges, and accurate prevalence estimates are essential for effective disease control.
  • The study assessed the agreement of diagnostic test results for QF and RVF in both humans and livestock across various labs and test types, using samples collected from rural Chad.
  • Findings indicated fair to moderate inter-laboratory agreement in test results, highlighting that demographic factors such as age and location significantly influence test outcomes, emphasizing the importance of considering these variables in future epidemiological research.
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The present study investigated the seropositivity rate of Hepatitis E virus (HEV) in domestic and working animals in Namibia, which included dogs, cats, horses, and donkeys. HEV poses a growing threat as a significant cause of human hepatitis globally and has several genotypes of varying zoonotic potential. As epidemiological data on the seroprevalence of HEV in Namibia is scarce, a serosurvey was conducted on archived serum samples of 374 dogs, 238 cats, 98 horses, and 60 donkeys collected between 2018 and 2022 from different regions, to assess the potential of these animals as sources of HEV infection.

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Hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide. Up to now, no approved treatment nor a globally licensed vaccine is available. Several recombinant HEV vaccines have been developed to protect against HEV infection in humans, including the commercially available Hecolin vaccine, which are mainly based on HEV genotype 1.

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Hepatitis E virus (HEV) is the main cause of acute hepatitis in humans worldwide and is responsible for a large number of outbreaks especially in Africa. Human infections are mainly caused by genotypes 1 and 2 of the genus , which are exclusively associated with humans. In contrast, viruses of genotypes 3 and 4 are zoonotic and have their main reservoir in domestic and wild pigs, from which they can be transmitted to humans primarily through the consumption of meat products.

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Hepatitis E virus (HEV) is transmitted by the fecal route, usually through contaminated water in humans and/or infected animals, especially pigs. The objective of this study was to evaluate the level of anti-HEV antibodies in a panel of pig sera and to identify HEV in pig feces in farms. The presence of HEV antibodies was tested by an in-house ELISA and a commercial ELISA IDvet.

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