Publications by authors named "M EL FEKI"

Introduction: Nemaline myopathy (NM), also known as Nemalinosis, is a rare congenital muscle disease with an incidence of 1 in 50000. It is characterized by nemaline rods in muscle fibers, leading to muscle weakness. We reported a case of NM revealed by cardiac involvement, and we highlighted the challenges in diagnosing this condition as well as its poor prognosis.

View Article and Find Full Text PDF

Background/objectives: Despite the abundant body of evidence linking high-intensity interval training (HIIT) to cardiometabolic markers, little is known about how HIIT affects liver enzymes, particularly in obese adolescents. This study aimed to investigate the effects of HIIT on metabolic dysfunction-associated steatotic liver disease (MASLD)-related biomarkers in overweight/obese adolescent girls.

Methods: Thirty-three overweight/obese adolescent girls (age, 17.

View Article and Find Full Text PDF

Olive mill wastewater (OMWW), a byproduct of olive oil extraction, constitutes a natural resource of phenolic compounds. Hydroxytyrosol (HT), the predominant compound, was reported to have antioxidant, anti-inflammatory, and neuroprotective effects. This research aims to evaluate the effect of OMWW bioproduct rich in HT on retinal glial function, glutamate metabolism, and synaptic transmission alterations mediated by hyperglycemia and dyslipidemia in high-calorie diet (HCD)-induced diabetic retinopathy (DR) in Psammomys obesus.

View Article and Find Full Text PDF
Article Synopsis
  • Psoriasis is a common autoimmune skin disease, but its exact cause is still unclear; this study explores whether specific biomarkers can indicate the presence and severity of the condition.
  • The research focuses on the relationship between serum levels of VEGF, MMP-9, and TIMP-2 in 115 psoriatic patients compared to 51 controls, using ELISA methods for measurement.
  • Findings show that while VEGF has low effectiveness in distinguishing between psoriasis variants, the combination of TIMP-2 and inflammation Z-score significantly improves discriminative power, highlighting the role of inflammation and tissue damage in the disease's progression.
View Article and Find Full Text PDF
Article Synopsis
  • - This study investigates the link between maternal fatty acid (FA) levels during pregnancy and the risk of neural tube defects (NTDs), assessing various nutrient levels like vitamin D, homocysteine, vitamin B, and folate in relation to the cases.
  • - Results show that women with NTD cases had higher levels of specific fatty acids (like heptadecanoic and arachidonic acid) and lower levels of omega-3 polyunsaturated fatty acids (n-3 PUFA) compared to controls.
  • - Additionally, maternal 25-hydroxyvitamin D (25(OH)D) was found to positively correlate with certain polyunsaturated fatty acids, while RBC folate levels were negatively correlated
View Article and Find Full Text PDF