Publications by authors named "M E Velthuizen"
Importance: Knowledge about the prevalence and tumor types of CDKN2A-related melanoma-astrocytoma syndrome (MAS) is limited and could improve disease recognition.
Objective: To estimate the prevalence and describe the tumor types of MAS.
Design, Setting, And Participants: This retrospective cohort study analyzed all available MAS cases from medical centers in the US (2 sites) and Europe (2 sites) and from biomedical population genomic databases (UK Biobank [United Kingdom], Geisinger MyCode [US]) between January 1, 1976, and December 31, 2020.
Background: Pre-test genetic counseling of patients with breast cancer is increasingly being offered by non-genetic healthcare professionals. We aimed to evaluate the experiences of patients with breast cancer receiving pre-test genetic counseling from a non-genetic healthcare professional (i.e.
View Article and Find Full Text PDFBackground: Pre-test genetic counseling for patients with breast cancer is increasingly being provided by nongenetic healthcare professionals. We evaluated the attitudes, knowledge, and self-efficacy of surgeons, oncologists, and nurses regarding mainstream genetic testing and the feasibility to incorporate pre-test genetic counseling into routine care.
Methods: We offered an online training to healthcare professionals from 13 hospitals and implemented a mainstream genetic testing pathway in 11/13 (85%) hospitals.
Article Synopsis
- Researchers studied how genetic testing affects women with ovarian cancer and how it differs when done by regular doctors versus genetic specialists.
- They compared two groups of patients: one that got counseling from gynecology doctors and another from genetic experts, and gathered their thoughts through questionnaires.
- While participation was high, the knowledge about genetics and feelings of anxiety were similar in both groups, but the regular doctors discussed cancer risks less and patients felt more regret about their testing decisions.
Objective: Germline genetic testing is increasingly offered to patients with epithelial ovarian cancer by non-genetic healthcare professionals, so called mainstream genetic testing. The aim of this study was to evaluate the effect of implementing a mainstream genetic testing pathway on the percentage of newly diagnosed patients with epithelial ovarian cancer to whom genetic testing was offered and the genetics-related healthcare costs.
Methods: The possible care pathways for genetic counseling and testing and their associated costs were mapped.