Arsenic is a ubiquitous toxic metalloid causing serious health problems. Speciation analysis of arsenic in human urine provides valuable insights for large-scale epidemiological studies and informs on sources of exposure as well as human metabolism. The Multi-Ethnic Study of Atherosclerosis (MESA) is a valuable cohort for assessing chronic low-moderate arsenic exposure and health effects in an ethnically diverse US population.
View Article and Find Full Text PDFBackground: American Indian populations have experienced marked disparities in respiratory disease burden. Extracellular vesicle-encapsulated microRNAs (EV-miRNAs) are a novel class of biomarkers that may improve recognition of lung damage in indigenous populations in the United States.
Research Question: Are plasma EV-miRNAs viable biomarkers of respiratory health in American Indian populations?
Study Design And Methods: The Strong Heart Study is a prospective cohort study that enrolled American Indian patients aged 45 to 74 years.