Role of ALT Perforator Flaps in Head and Neck Reconstruction.

Background: The anterolateral thigh flap is a versatile flap that offers many advantages. These include a long and reliable pedicle that enables a wide arc of rotation, the possibility to harvest a large skin area, raising the flap with underlying fascia and minimal donor site morbidity. The purpose of this study is to show better esthetics and function with the use of ALT perforator flap in head and neck region.

Protein phosphatase EYA1 regulates the dephosphorylation and turnover of BCL2L12 to promote glioma development.

Glioma is the most prevalent and deadly type of intracranial tumor. Understanding the molecular drivers and their underlying mechanisms in glioma development is urgently needed. EYA1 is a unique protein phosphatase that drives gliomagenesis, yet its substrates remain largely uncharacterized.

Irx3/5 Null Deletion in Mice Blocks Cochlea-Saccule Segregation and Disrupts the Auditory Tonotopic Map.

A gene cadre orchestrates the normal development of sensory and non-sensory cells in the inner ear, segregating the cochlea with a distinct tonotopic sound frequency map, similar brain projection, and five vestibular end-organs. However, the role of genes driving the ear development is largely unknown. Here, we show double deletion of the Iroquois homeobox 3 and 5 transcription factors (Irx3/5 DKO) leads to the fusion of the saccule and the cochlear base.

Efficacy of Reso-Pac in Wound Healing After Surgical Removal of Impacted Mandibular Third Molars: A Clinical Study.

Introduction: Extraction wounds in oral cavity are usually self-healing. But, this wound healing is hindered because of factors such as saliva, blood, plaque, food debris which causes post-operative infection and pain due to microbial colonization. Placement of periodontal dressings such as zinc oxide eugenol or methyl methacrylate polymer would provide protection up to some extent despite leaving the site without any dressing, but it has disadvantage of difficulty in removing.