Publications by authors named "M E Santolaya"
Unlabelled: Cancer remains one of the most important diseases in public health.
Objective: To estimate 5-year survival in pediatric cancer patients affected by FN, according to clinical-demographic variables.
Patients And Method: Survival, prognostic, and analytical study with historical cohort.
Article Synopsis
- This study examined the genetic makeup of Neisseria meningitidis strains from Chilean children using whole-genome sequencing (WGS) to assess potential vaccine effectiveness.* -
- Out of 42 strains analyzed, the most common types were MenB and MenW, with findings indicating varying levels of predicted vaccine coverage using tools like gMATS and MenDeVAR.* -
- The results revealed significant genetic variability among Chilean strains compared to those in other countries, which limits the ability to predict vaccine coverage accurately with existing methods.*
Background: Invasive fungal diseases (IFD) are high morbidity and mortality infections in children with cancer suffering episodes of high-risk febrile neutropenia (HRFN). IFD epidemiology has changed in the last two decades, with an increasing incidence in recent years due to the growing number of immunocompromised children at risk for IFD. The aim of this study was to evaluate the incidence of IFD in children with cancer in the period 2016-2020 compared to 2004-2006 in six hospitals in Chile.
View Article and Find Full Text PDFPurpose Of Review: The scope of this review is to understand the epidemiology and potential role of respiratory viral infections in children with cancer and febrile neutropenia, as well as in children, undergoing hematopoietic stem cell transplantation. Early detection of respiratory viral infections through molecular diagnostic techniques has allowed recent randomized clinical studies to advance the possibility of more rational use of antimicrobials in this susceptible population.
Recent Findings: Progress has been made in the early detection of respiratory viruses in episodes of fever and neutropenia in children with cancer.
Invasive fusariosis (IF) is a life-threatening opportunistic infection that affects vulnerable hosts. We conducted a multicenter and multinational retrospective study to characterize the natural history and clinical management of IF in pediatric cancer patients. We selected patients <18 years old who were sequentially hospitalized in 10 Latin American medical centers with a diagnosis of IF between 2002 and 2021.
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