Explorative study on the value of hepcidin in predicting iron non-responsiveness in paediatric inflammatory bowel disease.

Background: In a considerable proportion of anaemic children with inflammatory bowel disease (IBD), haemoglobin (Hb) does not normalise after iron therapy. We evaluated the added value of novel iron markers (hepcidin and soluble transferrin receptor [sTfR]) as compared to traditional iron markers (ferritin and transferrin saturation [TSAT]) to determine the best strategy for the prediction of non-responsiveness to iron suppletion.

Methods: In this secondary analysis of prospectively collected data, we measured iron markers in anaemic children (Hb Z-score < -2.

Evaluation of automated microscopy sediment analysis in urinary tract infection screening: a practical insight in adjusting fixed cut-off values for urine culture.

Purpose: The aim of our study was to evaluate a procedure in which urine culture was only being performed based on fixed cut-off values of urine sediment analysis with intention to prevent unnecessary negative urine cultures.

Methods: From January 2018 to August 2018, all urine samples from patients visiting the urology outpatient department were analyzed. Urine culture was only performed if urine sediment contained more than 130 bacteria per microliter and/or more than 50 leukocytes per microliter.

Comparison of Two Tuberculosis Infection Tests in a South American Tertiary Hospital: STANDARD F TB-Feron FIA vs. QIAreach QuantiFERON-TB.

Introduction: Tuberculosis (TB) is one of the most prevalent respiratory diseases in the world. In 2020 there were at least 9.9 million new infections, with 1.

Presenting wicked problems in a science museum: A methodology to study interest from a dynamic perspective.

Science centers and science museums have an important social role in engaging people with science and technology relevant for complex societal problems-so called wicked problems. We used the case of personalized medicine to illustrate a methodology that can be used to inform the development of exhibitions on such wicked problems. The methodology that is presented is grounded in dynamic theories of interest development that define interest as a multidimensional construct involving knowledge, behavior (personal and general) value, self-efficacy, and emotion.