Publications by authors named "M E Olivera"

The management of wounds primarily revolves around pain relief, effective infection control and the promotion of tissue regeneration to prevent complications like chronic skin wounds. While polymeric bioactive films are innovative alternatives to conventional wound dressings, there exists a dearth of guidance regarding their quality control. This underscores the imperative need to establish precise critical quality attributes, a task undertaken within this study using an antibiotic-anesthetic film as a model.

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Objective: The Epilepsy Self-Stigma Scale (ESSS) has been developed in Japan for patients with epilepsy (PWE). We aimed to validate the scale in Spanish and examine its validity and reliability.

Methods: The transcultural adaptation of the ESSS was conducted using translation and back-translation, along with pilot testing and an expert panel review.

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  • - In the KEYNOTE-826 study, pembrolizumab combined with chemotherapy significantly boosted overall survival (OS) and progression-free survival (PFS) in patients with advanced cervical cancer, with specific attention to those using bevacizumab.
  • - The analysis included 617 patients, with a majority excluded from bevacizumab due to medical reasons; outcomes showed that those receiving pembrolizumab generally had better survival metrics, regardless of bevacizumab use.
  • - Patients on pembrolizumab experienced a high rate of severe side effects, with 74% suffering grade ≥3 treatment-related adverse events in the bevacizumab group.
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  • Differentiating tachycardia-induced cardiomyopathy (TIC) from dilated cardiomyopathy (DCM) is difficult for patients with heart failure (HF) and left ventricular dysfunction caused by supraventricular tachyarrhythmia (SVT).
  • A study analyzed 43 patients admitted for HF due to SVT; those whose left ventricular ejection fraction (LVEF) improved were classified as TIC, while those with persistent low LVEF were classified as DCM.
  • Key findings showed that diabetes, late gadolinium enhancement (LGE), low left ventricular peak systolic velocity, and specific right ventricular displacement measurements could help predict LVEF recovery and distinguish between TIC
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  • A 40-year-old male from Vereda Buenos Aires presented to the emergency department with symptoms including fever, headache, and dysuria, initially diagnosed with a urinary tract infection.
  • After five days, he was confirmed to have acute phase Chagas disease due to a positive result for Trypanosoma cruzi.
  • The patient received treatment with nifurtimox and benznidazole, and health authorities conducted investigations in the community, identifying five other symptomatic individuals, but further tests for Chagas were negative, leading to health education initiatives to prevent disease spread.
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