Associations between dual-task walking and cognitive impairment in people attending a cognitive diagnostic clinic.

Objectives: Dual-task walking performance is an early marker of dementia. However, there is uncertainty about which measure of the dual-task test is a better marker. The objective of this study was to determine which dual-task measure best differentiates between normal cognition, mild cognitive impairment (MCI) and dementia.

Wernicke encephalopathy in a pediatric patient with cannabinoid hyperemesis: A novel case report.

This case report details a novel case of Wernicke encephalopathy (WE) in a 16-year-old boy with obesity and chronic cannabis use. Despite the absence of alcohol use disorder, this adolescent developed classic symptoms of WE, challenging the conventional diagnostic framework. Clinical suspicion for WE was supported by typical magnetic resonance imaging findings, low thiamine levels and rapid clinical improvement postintravenous thiamine supplementation.

Tracking of Systemic Lupus Erythematosus (SLE) Longitudinally Using Biosensor and Patient-Reported Data: A Report on the Fully Decentralized Mobile Study to Measure and Predict Lupus Disease Activity Using Digital Signals-The OASIS Study.

(1) Objective: Systemic lupus erythematosus (SLE) is a complex disease involving immune dysregulation, episodic flares, and poor quality of life (QOL). For a decentralized digital study of SLE patients, machine learning was used to assess patient-reported outcomes (PROs), QOL, and biometric data for predicting possible disease flares. (2) Methods: Participants were recruited from the LupusCorner online community.

Gram-Positive Bacteria Cell Wall Peptidoglycan Polymers Activate Human Dendritic Cells to Produce IL-23 and IL-1β and Promote T17 Cell Differentiation.

Gram-positive bacterial infections are a major cause of organ failure and mortality in sepsis. Cell wall peptidoglycan (PGN) is shed during bacterial replication, and PGN promotes a sepsis-like pathology in baboons. Herein, we determined the ability of polymeric PGN free from TLR ligands to shape human dendritic cell (DC) responses that are important for the initiation of T cell immunity.

Peer charity donation, gratitude, and self-esteem among left-behind children.

Previous research suggests that receiving a charity donation could induce gratitude but threaten self-esteem. We investigated if peer charity donations from typical children benefit or harm the mental health of their left-behind children (LBC) classmates. We recruited children at a school (i.