Publications by authors named "M E Molina de Bernadou"

The study deals with the infectious diseases department of the university hospital of Bordeaux where most of the AIDS patients in south western France are admitted. In 1986, the department counted 64 admissions (and readmissions) from 35 AIDS patients and 1376 admissions (and readmissions) from 707 other patients. Taking into account admissions of AIDS patients into other hospital departments, the average cost of a hospital day of an AIDS patient was estimated at 1815 French francs in 1986.

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The relapse rate after short course chemotherapy is usually assessed by cases that are available for analysis, with a delay which rarely exceeds 3 years from the time of instituting therapy. This level may be disputed if too many are lost to follow up or non-compliers appearing late. To understand the true failure rate we strove to trace every patient in a trial carried out between 1969 and 1973, consisting of three groups of patients treated with the same chemotherapy: Isoniazid (450 mg/day), Rifampicin (600 mg/day) given every day but for differing durations: 6 months (Group A), 9 months (Group B), 12 months (Group C), with either daily Ethambutol or Streptomycin in addition for the first three months.

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The authors present scales of reference theoretical values for children and peak expiratory output (V 50 and V 25), as well as FEV1 and vital capacity obtained by flow-volume curves. After a description of the equipment (adaptable to on-the-spot epidemiological studies), the reference population (537 children, male and female, 6-16 years old), and the method of curve applications, the statistical basis for devising the scale was analyzed. Under study were the following topics: assuming an exponential regression model, advantages of the consideration of two reference parameters (age and size), or of one (size), which was the solution adopted finally to construct the scale.

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The aim of this work was to evaluate the clinical effectiveness of antimicrobial vaccination in patients suffering from chronic bronchopathies. We proposed this vaccination to 40 patients divided into two groups: one received either the bacterial suspension or ribosomal extracts; the other was given a Placebo. The effectiveness of the vaccination in reflected mainly by the statistically significant decrease in the number of infectious outbreaks and in antibiotic consumption in winter as compared to a control group receiving only a Placebo.

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The first results of a survey involving 1950 children from 6 to 12 years old living in Bordeaux are presented here. For 280 of them, who had attacks of asthma or showed other closely related signs, a questionnaire was filled out by the parents. On this basis, the main features of the disease, as well as the ORL bronchial and allergological course, were specified for a representative epidemiological population (with a distinction between actual asthma and disappeared asthma, distribution according to sex and age of the first attack).

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