Publications by authors named "M E Martenson"
Article Synopsis
- * The body regulates iron levels through intestinal absorption, as excretion is inefficient; aging can disrupt this balance, leading to deficiencies or excess iron.
- * Regular assessment of iron status and adherence to daily intake guidelines is crucial for older adults to maintain healthy iron levels and minimize health risks.
By definition, aging is a natural, gradual and continuous process. On the other hand, frailty reflects the increase in vulnerability to stressors and shortens the time without disease (health span) while longevity refers to the length of life (lifespan). The average life expectancy has significantly increased during the last few decades.
View Article and Find Full Text PDFAltered mitochondrial quality and function in muscle may be involved in age-related physical function decline. The role played by the autophagy-lysosome system, a major component of mitochondrial quality control (MQC), is incompletely understood. This study was undertaken to obtain initial indications on the relationship between autophagy, mitophagy, and lysosomal markers in muscle and measures of physical performance and lower extremity tissue composition in young and older adults.
View Article and Find Full Text PDFPatients with functional pain disorders often complain of generalized sensory hypersensitivity, finding sounds, smells, or even everyday light aversive. The neural basis for this aversion is unknown, but it cannot be attributed to a general increase in cortical sensory processing. Here, we quantified the threshold for aversion to light in patients with fibromyalgia, a pain disorder thought to reflect dysregulation of pain-modulating systems in the brain.
View Article and Find Full Text PDFObjective: To compare the effect of hyaluronic acid (HA) intra-articular knee injections on pain and functional outcomes in persons with knee osteoarthritis (OA) over 6 months, and to determine whether or not changes in functional pain are related to improvements in quality of life.
Design: A prospective cohort study.
Setting: A research laboratory in an academic medical center.