Publications by authors named "M E Maguire"

Background/objectives: The projected increase from 58 million older adults in 2022 to 82 million by 2050 in the United States highlights the urgency of preparing nursing students to care for this aging population. However, studies reveal negative attitudes among nursing students toward older adults. A three-phased educational intervention that included an artificial intelligence (AI)-driven virtual simulation was implemented to address this.

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Purpose: To report the design of FLuorometholone as Adjunctive MEdical therapy for TT surgery (FLAME) trial.

Design: Parallel design, double-masked, placebo-controlled clinical trial with 1:1 randomization to fluorometholone 0.1% eye drops twice daily or placebo twice daily for 4 weeks in eyes undergoing trachomatous trichiasis (TT) surgery for assessing the efficacy, safety, and cost-effectiveness of fluorometholone 0.

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The design of supramolecular hydrogels comprising aligned domains is important for the fabrication of biomimetic materials and applications in optoelectronics. One way to access such materials is by the self-assembly of small molecules into long fibres, which can be aligned using an external stimulus. Out-of-equilibrium supramolecular gels can also be designed, where pre-programmed changes of state can be induced by the addition of chemical fuels.

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Article Synopsis
  • Carbapenemase-producing Enterobacterales (CPE) are multidrug-resistant bacteria that can spread their resistance genes via mobile genetic elements, complicating infection control efforts.
  • A study in Galway, Ireland involved whole-genome sequencing of CPE samples from patients and wastewater to understand the distribution and characteristics of these organisms and their resistance genes.
  • Findings revealed that most resistance genes were found on plasmids, with specific plasmid types associated with different CPE strains, highlighting the genetic mechanisms facilitating the spread of resistance between humans and the environment.
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Objective: To determine whether translocation carriers have a reduced number of usable blastocysts compared with infertile controls.

Design: Retrospective cohort study.

Setting: Single infertility practice.

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