Publications by authors named "M E Machado-Duque"

Background: Mycophenolate mofetil is used for the prevention of solid organ transplant rejection and for other indications, such as systemic lupus erythematosus (SLE).

Objective: To determine the prescription patterns of mycophenolate mofetil in a group of Colombian patients.

Methods: This was a cross-sectional study of patients receiving mycophenolate mofetil between 2021 and 2022.

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Article Synopsis
  • - The study investigates the prescription patterns of noninsulin antidiabetic medications among 155,381 Colombian patients with type 2 diabetes mellitus (T2DM), primarily focusing on the most commonly prescribed drugs and their usage in combination therapy.
  • - Metformin emerged as the most frequently prescribed antidiabetic, followed by empagliflozin, sitagliptin, linagliptin, and dapagliflozin, with a significant portion of patients (55.5%) receiving combinations of two or three medications.
  • - Despite advancements in treatment guidelines, many T2DM patients with related cardiovascular conditions are not receiving optimal antidiabetic therapy, indicating a need for better access to drugs that might reduce cardiovascular risk, like sodium
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Human immunodeficiency virus (HIV) is a global public health problem. Coinfections in HIV patients are frequent complications that increase their mortality. The aim of this study was to assess coinfections and in-hospital mortality in a group of patients infected with HIV in Colombia.

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Objective: Insomnia is a frequent and difficult disease to treat. The objective was to determine the pharmacological management of a group of patients diagnosed with acute and chronic insomnia.

Methods: This is a cross-sectional study that identified patterns of prescription of drugs for outpatient use in patients with insomnia from a population database of 8.

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Article Synopsis
  • The study aimed to evaluate how timely children under 6 in Colombia received vaccinations as per the country's Expanded Immunization Program between 2014 and 2019.
  • A total of 3,370,853 children were analyzed, revealing over 80% received most vaccines on time, but lower rates were noted for yellow fever (17%) and seasonal influenza (42%).
  • Significant differences in vaccination timeliness were observed, particularly with indigenous children showing lower rates (65.8%) compared to the general population (78.6%), highlighting the need for targeted strategies to improve immunization access for all groups.*
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