Publications by authors named "M E M M Bos"

Purpose: Adolescent and young adult (AYA) malignant brain tumour (BT) survivors are at risk of adverse health outcomes, which may impact their health-related quality of life (HRQoL). This study aimed to investigate the (1) prevalence of physical and psychological adverse health outcomes, (2) the HRQoL, and (3) the association of adverse health outcomes and HRQoL among long-term AYA-BT survivors. Adverse health outcomes and HRQoL were compared to other AYA cancer (AYAC) survivors.

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Environmental protection, especially fouling protection, is a very topical and wide-ranging issue. This review explores the development, molecular design, and nanoarchitectonics of sol-gel-based hybrid coatings for antifouling applications. These coatings combine inorganic and organic materials, offering enhanced stability and adaptability, making them ideal for protecting surfaces from fouling.

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Objective: There is a need for improved diagnostic tools in Amyotrophic Lateral Sclerosis (ALS). Our objective was to assess muscle ultrasound as a diagnostic tool in patients with ALS and determine a simplified screening protocol to aid implementation in clinical practice.

Methods: Ultrasound of bulbar and limb muscles was prospectively performed on all patients referred to a single centre with suspected ALS.

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Physical activity has been associated with a lower risk of various types of cancer and reduced cancer-specific mortality. Less is known about its impact on pancreatic cancer. The aim of this systematic review and meta-analysis was to summarize evidence on the association between physical activity and pancreatic cancer risk and mortality.

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Article Synopsis
  • Cortical hyperexcitability in amyotrophic lateral sclerosis (ALS) is linked to complex interactions between cortical interneurons, with this study examining GABA-ergic dysfunction via a combination of transcranial magnetic stimulation (TMS) and EEG.
  • In 21 ALS patients, TMS-EEG results showed significant differences in the transcranial evoked potential (TEP) components compared to healthy controls, indicating impaired cortical inhibitory function.
  • Notably, changes in TEP components correlated with muscle weakness and longer disease duration, highlighting the role of disrupted GABA-ergic circuits in the progression of ALS.
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