Publications by authors named "M E Liebeskind"
Importance: Although overactive bladder (OAB) is a common condition, affecting 16% of Americans, few patients continue on to advanced therapies. Furthermore, procedural therapies like intravesical onabotulinum toxin-A (BTX-A), which require ongoing repeat treatments, have discontinuation rates ranging from 25% to 51%.
Objectives: This study sought to investigate factors associated with dis-continuation of BTX-A injections for idiopathic OAB among a diverse urban population.
Purpose Of Review: The treatment of many distal radius fractures has shifted from casting to splinting or the application of a soft dressing. This review includes a review of the types of pediatric distal radius fractures and the most recent literature on the management of these injuries.
Recent Findings: Many nondisplaced distal radius fractures may be treated with removable splints or bandages.
Article Synopsis
- Lateral flow assays (LFA) effectively detect antibodies to SARS-CoV-2 proteins shortly after infection, and this study evaluated their performance in both immunocompetent adults and those with chronic inflammatory diseases post-vaccination.
- Results showed that LFA identified anti-S antibodies in 100% of immunocompetent participants and 87.3% of chronic inflammatory disease participants, with lower scores in immunosuppressed individuals.
- The study concludes that LFA presents a practical, low-resource method for antibody detection, making it valuable for outpatient settings compared to traditional laboratory analyses.
Most human genetic variation is classified as variants of uncertain significance. While advances in genome editing have allowed innovation in pooled screening platforms, many screens deal with relatively simple readouts (viability, fluorescence) and cannot identify the complex cellular phenotypes that underlie most human diseases. In this paper, we present a generalizable functional genomics platform that combines high-content imaging, machine learning, and microraft isolation in a method termed "Raft-Seq".
View Article and Find Full Text PDFArticle Synopsis
- The emergence of new SARS-CoV-2 variants threatens the effectiveness of immunity from previous infections or vaccinations.
- To tackle this issue, the NIH launched the SARS-CoV-2 Assessment of Viral Evolution (SAVE) program for real-time assessment of variant risks that might impact transmission and vaccine efficacy.
- The program focuses on gathering and analyzing data on emerging variants and their effects on immunity, using animal models, while also addressing future challenges in monitoring rapidly evolving viruses.